Primary Autologous Stem Cell Transplantation for Unilateral Primary Central Nervous System Lymphoma–Ophthalmic Variant (Primary Vitreoretinal Lymphoma)

Purpose: To describe the long-term outcomes of 2 cases primary autologous stem cell transplantation (ASCT) for treatment central nervous system lymphoma–ophthalmic variant (PCNSL-O) or vitreoretinal lymphoma (PVRL). Methods: Two and their findings were analyzed. A review histopathology, systemic treatment, multimodal ocular imaging was performed. Results: 52-year-old woman 56-year-old referred vitritis retinal lesions suspicious PCNSL-O. The initial vitreous biopsies inconclusive. Both patients had subsequent chorioretinal that confirmed diagnosis diffuse large B-cell lymphoma. No involvement found on workup. received intravitreal chemotherapy followed by ASCT, both remained in complete remission 7 8 years later. Conclusions: These show survival diagnosed with PVRL when PCNSL, is